Clearance of theophylline is decreased by
WebOct 5, 2024 · Discontinuation of a concomitant drug that inhibits theophylline clearance will result in decreased serum theophylline concentrations, unless the theophylline dose is appropriately increased. The drugs listed in Table III have either been documented not to interact with theophylline or do not produce a clinically significant interaction ( i.e ... WebAs compared to 19 normal subjects, these patients had a prolonged plasma half-life (mean, 25.6 vs. 6.7 hours) and a decreased plasma clearance (mean, 0.042 vs. 0.062 liter [kg-1] hr-1). Volumes of ...
Clearance of theophylline is decreased by
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WebNote: In addition to the factors listed above, theophylline clearance is increased and half-life decreased by low carbohydrate/high protein diets, parenteral nutrition, and daily consumption of charcoal-broiled beef. A high carbohydrate/low protein diet can decrease the clearance and prolong the half-life of theophylline. WebDosage Guidelines for Theophylline in Children Older Than 6 Months and Adults Who Have No Risk Factors for Decreased Theophylline Clearance. Transient effects similar to those of caffeine, such as ...
WebTheophylline: Clearance decreased; reduce theophylline dose by one-third (5.8). Warfarin: Plasma concentrations increased and prothrombin times prolonged; monitor … WebIn addition to bronchodilation, theophylline increases diaphragmatic contractility, increases mucociliary clearance, and exerts some antiinflammatory effects. Theophylline is a general central nervous system stimulant and specifically …
WebMarkedly depressed theophylline clearances (serum half-life up to > 60 hours) in patients with hepatic disease (especially cirrhosis) Reversible, transient decreased clearance with Heart failure Pneumonia Acute viral respiratory infection Smoking history (increased theophylline clearance with tobacco and marijuana smoking) WebIn addition to the factors listed above, theophylline clearance is increased and half-life decreased by low carbohydrate/high protein diets, parenteral nutrition, and daily consumption of charcoal-broiled beef. A high carbohydrate/low protein diet can decrease the clearance and prolong the half-life of theophylline. Page 3 of 20
WebFeb 26, 2013 · Decreased clearance is also seen with several drugs, including erythromycin, quinolone antibiotics (ciprofloxacin, but not ofloxacin), allopurinol, …
WebAll patients in this study were non-smokers with normal hepatic and renal function, and they were not given any other drugs that could affect the clearance of theophylline. Results: … jesu bambino sheet musicWebApr 26, 2024 · In adolescents ≥ 16 years and adults, including the elderly, the final theophylline dose should not exceed 400 mg/day in the presence of risk factors for reduced theophylline clearance (see WARNINGS) or … jesu bambino yonWebNov 2, 1983 · The elimination of theophylline (clearance, half-life) was investigated in 50 patients with chronic congestive heart failure (grade III/IV) and in 20 controls. The cardiac diagnosis was based on clinical and hemodynamic parameters. Patients with congestion of the liver showed a significant reduction …. jesu band merchWebAminophylline is a combination of theophylline and ethylenediamine. Ethylenediamine is inactive; it increases the solubility of theophylline in water. ... and to neonates and the elderly, since in all of these circumstances theophylline clearance may be decreased, resulting in increases in serum-theophylline concentrations and serum half-life ... lampa zepteraWebThe clearance of theophylline is decreased by an average of 30% in healthy elderly adults (>60 yrs) compared to healthy young adults. Theophylline clearance may be … jesu barndomWebIncreased risk of hyperkalemia when used concurrently with an ACEI or ARB in presence of decreased creatinine clearance. Use with caution in patients on ACEI or ARB and decreased creatinine clearance. Low Strong. ... Theophylline. Cimetidine. Increased risk of theophyllinetoxicity. Avoid. Moderate. Strong. Theophylline. Cipro. floxacin ... jesu bambino luciano pavarottiWebFeb 1, 1983 · Cimetidine decreased the apparent total body clearance of theophylline an average of 29 percent (range: 18-47 percent) from 39.5±11.7 to 28.1±3.4 ml/hr/kg (p<0.02X There was no significant change in the volume of distribution; however, the terminal half-life increased from 7.3 ± 1.5 to 10.1 ± 2.1 hr (p<0.01) during A and A-C, respectively. jesu bambino song lyrics