WebFeb 10, 2016 · The NF-κB inhibitory and cytotoxic activity evaluation disclosed that dysiherbol A (1) showed potent activity with respective IC50 values of 0.49 and 0.58 μM, which were about 10-fold and 20-fold more potent than those of dysiherbols B (2) and C (3), which feature hydroxy and ketone carbonyl groups at the C-3 position. WebOct 13, 2024 · Published 13 October 2024. Chemistry. Journal of the American Chemical Society. Herein, we report the enantioselective total synthesis of dysiherbols A, C, and D, a unique group of 6/6/5/6/6 pentacyclic quinone/hydroquinone sesquiterpenes, featuring a photo-induced quinone-alkene [2 + 2] cycloaddition and a tandem [1,2]-anionic …
Chemistry Tree - Zhaoyong Lu
WebJun 5, 2024 · An iodine-promoted sunlight-induced olefin Z/E isomerization reaction together with a palladium-catalyzed direct cross-coupling reaction of a drimanal hydrazone and an iodobenzaldehyde, without touching the aromatic aldehyde group, facilitated a divergent and expeditious access to bioactive marine natural products siphonodictyal B, corallidictyals … WebJun 1, 2024 · In 2016 Jiao et al. reported the isolation and structural elucidation of dysiherbols A–C (1–3) and dysideanone E (4) as metabolites of the sponge Dysidea sp. … lithium handelsname
Divergent total synthesis of the revised structures of marine anti ...
WebJun 25, 2024 · The obtained pentacyclic compound (corresponding to an anhydride of the originally suggested structure for dysiherbol A) showed identical spectroscopic data as … WebAcer diabolicum, the horned maple or devil maple, is a species of maple that is endemic to central and southern Japan. There it is known as カジカエデ, kaji kaede or オニモミジ, … WebThe neo-trans-clerodane natural product, (−)-methyl barbascoate 1, has been synthesized for the first time starting from the known ketone 6 derived from (R)-(−)-Wieland−Miescher ketone analogue 5. lithium handheld vacuum