Solubility of gemcitabine hydrochloride
WebJun 1, 2024 · Gemcitabine hydrochloride is soluble in water, slightly soluble in methanol, and practically insoluble in ethanol and polar organic solvents. Gemcitabine for Injection, USP is a sterile white to off-white lyophilized powder and available as 200 mg and 1 g single-dose vials for intravenous use only. WebGemcitabine HCl (Gemzar) ... *<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and …
Solubility of gemcitabine hydrochloride
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WebFeb 25, 2024 · The solution was then diluted 10× with a premade PBS solution of gemcitabine (hydrochloride salt) (12.65 mg/mL). Final concentrations of drugs were 10/1 mg/mL GT. CrEL drug suspensions were used within the same day of preparation due to instability. ... Whether a water soluble gemcitabine (Log P=−1.5) and insoluble paclitaxel ... WebGemcitabine hydrochloride (2′-Deoxy-2′,2′-difluorocytidine; dFdC ); >= 98% HPLC; This compound is a featured product for Apoptosis research; Gemcitabine is a widely used …
WebGemcitabine Hydrochloride is the hydrochloride salt of an analogue of the antimetabolite nucleoside deoxycytidine with antineoplastic activity. … WebJun 29, 2024 · Gemcitabine 1 g/m 2 (as 30-minute infusion) has been given on days 1 and 8 of each 21-day cycle; administered in combination with cisplatin (25 mg/m 2 as 1-hour …
WebSolubility: Soluble in DMSO at 12.5 mg/mL with slight warming; very poorly soluble in ethanol; soluble in water at 25 mg/mL with slight warming; buffers, ... Gemcitabine … WebGemcitabine hydrochloride (2′-Deoxy-2′,2′-difluorocytidine; dFdC ); >= 98% HPLC; This compound is a featured product for Apoptosis research; Gemcitabine is a widely used antineoplastic agent and antimetabolite; Gemcitabine is a widely used antitumor agents in both clinics and research labs;
WebApplication. It is intended to be used as a USP reference standard in specified quality tests and assays. Also used to prepare standard solutions in the assay and impurities analysis …
WebApr 1, 1999 · Reconstituted gemcitabine as the hydrochloride salt in the original vials is chemically stable at room temperature for 35 days but may develop crystals when stored … iphone supported carriersWebDec 2, 2013 · The release behavior of another anti-cancer drug gemcitabine from the PU matrix is quite different from that of PTX due to the extreme difference in water solubility between gemcitabine and PTX.PTX is practically insoluble in water, whereas gemcitabine is readily soluble in water and has a solubility of 1.55% [37,67]. iphone support uk numberWebApr 1, 1999 · Gemcitabine is a fluoro-cytidine analog with primarily antitumor activity and is administered intravenously [120]. Although its hydrochloride salt is well soluble in water … iphone supply and demandWebGemcitabine is a chemotherapeutic agent used as monotherapy or in combination with other anticancer agents. In combination with [carboplatin], it is indicated for the treatment … orange lily group hamiltonWebGeneral description. A bioavailable, moderately toxic, deoxyctytidine analog with anti-metabolite and anti-tumor properties. Shown to be effective against a variety of tumors … orange lights in the sky tonight 2022WebUse in Cancer. Gemcitabine hydrochloride is approved to be used alone or with other drugs to treat: Breast cancer that cannot be treated with or that did not respond to … orange lightweight jacket for womenWebGemcitabine Hydrochloride, CAS: 122111-03-9, is a deoxycytidine analog that inhibits ribonucleotide reductase & induces apoptosis. ... Gemcitabine Hydrochloride, sc-204763, … orange lights on motherboard